Medicana Bursa Hastanesi Hematoloji Uzman\u0131 Dr. \u00d6mer \u00d6nder, T\u00fcrkiye\u2019de bir milyonun \u00fczerinde beta talasemi ta\u015f\u0131y\u0131c\u0131s\u0131 ve yakla\u015f\u0131k 4000 civar\u0131nda beta talasemi hastas\u0131 oldu\u011funu s\u00f6yledi.<\/p>\n
Dr. \u00d6mer \u00d6nder, talasemi hakk\u0131nda bilgi vererek, \u201cTalasemi hemoglobin zincirlerinden birinin veya bir ka\u00e7\u0131n\u0131n hasarl\u0131 sentezi sonucu geli\u015fen, hipokrom mikrositer anemi ile karakterize bir grup hastal\u0131kt\u0131r. Talasemi hastal\u0131\u011f\u0131, olarak tan\u0131mlanan hemoglobin zincirlerinin az say\u0131da veya hi\u00e7 yap\u0131lamamas\u0131 ile ortaya \u00e7\u0131kar. Talasemiler sessiz ta\u015f\u0131y\u0131c\u0131 veya hafif anemi ile ortaya \u00e7\u0131kabildikleri gibi alt tipine g\u00f6re ciddi miktarda kan deste\u011fine de ihtiya\u00e7 duyabilmektedirler. Talasemi otosomal resesif ge\u00e7i\u015flidir yani \u00e7ekinik genlerle aktar\u0131l\u0131r. Hastal\u0131k olu\u015fmas\u0131 i\u00e7in tek bir geni ta\u015f\u0131mak yeterli de\u011fildir, anne ve babadan al\u0131nan genlerin ikisinin de hastal\u0131k ta\u015f\u0131y\u0131c\u0131 \u00f6zellikte olmas\u0131 gerekir. E\u011fer hastal\u0131k genini anne ve babadan sadece biri ta\u015f\u0131yorsa do\u011facak olan \u00e7ocuklar\u0131n y\u00fczde 50 ta\u015f\u0131y\u0131c\u0131 olma ihtimali vard\u0131r. E\u011fer hem anne hem baba ta\u015f\u0131y\u0131c\u0131 ise do\u011facak olan \u00e7ocuklarda y\u00fczde 50 ta\u015f\u0131y\u0131c\u0131 ve y\u00fczde 25 hasta olmal\u0131k ihtimali vard\u0131r. E\u011fer anne ya da babadan biri hasta di\u011feri ta\u015f\u0131y\u0131c\u0131 ise y\u00fczde 50 ta\u015f\u0131y\u0131c\u0131 ve y\u00fczde 50 hasta \u00e7ocuk sahibi olma riski vard\u0131r. Hasta bebek do\u011furma olas\u0131l\u0131\u011f\u0131 olan her \u00e7ift genetik dan\u0131\u015fmanl\u0131k i\u00e7in de\u011ferlendirilmelidir” dedi.<\/p>\n
Dr. \u00d6mer \u00d6nder, “Talasemi te\u015fhisi tam kan say\u0131m\u0131, periferik yayma, hemoglobin elektroforezi gibi kan testleri ile konulabilmektedir. Risk de\u011ferlendirilmesine g\u00f6re hastal\u0131\u011f\u0131n tan\u0131s\u0131n\u0131 netle\u015ftirmek i\u00e7in genetik \u00e7al\u0131\u015fmalar planlanabilir. Talasemide \u00e7e\u015fitli y\u00f6ntemlerle do\u011fum \u00f6ncesinde tan\u0131 koymaya prenatal te\u015fhis ad\u0131 verilmektedir. Prenatal tan\u0131 koryonik vill\u00fcs biyopsisi, amniosentez,kordosentez gibi y\u00f6ntemlerle yap\u0131labilmektedir. Koryonik vill\u00fcs biyopsisi ile di\u011fer y\u00f6ntemlere g\u00f6re daha erken te\u015fhis koymak m\u00fcmk\u00fcn olabilmektedir. Bu y\u00f6ntemlerle az miktarda da olsa d\u00fc\u015f\u00fck, kanama, erken do\u011fum ve enfeksiyon riskleri mevcuttur. Hastal\u0131\u011f\u0131n \u00f6zellikle s\u0131k g\u00f6r\u00fcld\u00fc\u011f\u00fc b\u00f6lgelerde evlilik \u00f6ncesi \u00e7iftlerin taranmas\u0131, toplumun akraba evliliklerinin riskleri hakk\u0131nda bilgilendirilmesi olduk\u00e7a \u00f6nemlidir. Ta\u015f\u0131y\u0131c\u0131l\u0131\u011f\u0131n y\u00fcksek olarak g\u00f6r\u00fcld\u00fc\u011f\u00fc b\u00f6lgelerde hasta ve ta\u015f\u0131y\u0131c\u0131 bireylerin akrabalar\u0131n\u0131n da ta\u015f\u0131y\u0131c\u0131l\u0131k a\u00e7\u0131s\u0131ndan de\u011ferlendirilmesi, e\u015flerin ikisinin de ta\u015f\u0131y\u0131c\u0131 olmas\u0131 durumunda e\u015flere dan\u0131\u015fmanl\u0131k verilmeli, genetik tan\u0131 merkezlerine y\u00f6nlendirilmeli ve gebelik \u00f6ncesinde gerekli tetkikler tamamlanmal\u0131d\u0131r. Ta\u015f\u0131y\u0131c\u0131 anne ve baba s\u00f6z konusu ise \u00e7iftler gebeli\u011fin ilk d\u00f6nemlerinde prenatal tan\u0131 a\u00e7\u0131s\u0131ndan doktora ba\u015fvurmal\u0131 ve gerekli tetkikleri yapt\u0131rmal\u0131d\u0131rlar. Talasemiler (Akdeniz anemisi) \u00f6nlenebilir irs\u00ee kan hastal\u0131klar\u0131n\u0131n ba\u015f\u0131nda gelir. \u00dclkemizde Akdeniz B\u00f6lgesi, Marmara ve Ege B\u00f6lgesinde talasemi ta\u015f\u0131y\u0131c\u0131l\u0131\u011f\u0131 \u00e7ok s\u0131k g\u00f6r\u00fclmektedir. Talasemiler sessiz ta\u015f\u0131y\u0131c\u0131 veya hafif anemi ile ortaya \u00e7\u0131kabildikleri gibi alt tipine g\u00f6re ciddi miktarda kan deste\u011fine de ihtiya\u00e7 duyabilmektedirler. E\u011fer hastal\u0131k genini anne ve babadan sadece biri ta\u015f\u0131yorsa do\u011facak olan \u00e7ocuklar\u0131n y\u00fczde 50 ta\u015f\u0131y\u0131c\u0131 olma ihtimali vard\u0131r. E\u011fer hem anne hem baba ta\u015f\u0131y\u0131c\u0131 ise, do\u011facak olan \u00e7ocuklar\u0131n y\u00fczde 50 ta\u015f\u0131y\u0131c\u0131 ve y\u00fczde 25 hasta olma ihtimali vard\u0131r. E\u011fer anne ya da babadan biri hasta di\u011feri ta\u015f\u0131y\u0131c\u0131 ise y\u00fczde 50 ta\u015f\u0131y\u0131c\u0131 ve y\u00fczde 50 hasta \u00e7ocuk sahibi olma riski vard\u0131r. Hasta bebek do\u011furma ihtimali olan her \u00e7ift genetik dan\u0131\u015fmanl\u0131k i\u00e7in de\u011ferlendirilmelidir\u201d diye konu\u015ftu.<\/p>\n","protected":false},"excerpt":{"rendered":"
MED\u0130CANA BURSA HASTANES\u0130 HEMATOLOJ\u0130 UZMANI DR. \u00d6MER \u00d6NDER, T\u00dcRK\u0130YE’DE B\u0130R M\u0130LYONUN \u00dcZER\u0130NDE BETA TALASEM\u0130 TA\u015eIYICISI VE YAKLA\u015eIK 4000 C\u0130VARINDA BETA TALASEM\u0130 HASTASI OLDU\u011eUNU S\u00d6YLED\u0130<\/p>\n","protected":false},"author":1,"featured_media":141418,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[1],"tags":[1332,31905,1440],"class_list":["post-141417","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-genel","tag-akdeniz","tag-anemisine","tag-dikkat"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"https:\/\/i0.wp.com\/www.tvturk.com\/wp-content\/uploads\/2019\/04\/akdeniz-anemisine-dikkat_bd64012.jpg?fit=666%2C1000","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/paKIfm-AMV","_links":{"self":[{"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/posts\/141417","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/comments?post=141417"}],"version-history":[{"count":0,"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/posts\/141417\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/media\/141418"}],"wp:attachment":[{"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/media?parent=141417"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/categories?post=141417"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/tags?post=141417"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}