50 ya\u015f \u00fczeri erkeklerde en s\u0131k g\u00f6r\u00fclen t\u00fcr olan prostat kanserinin tan\u0131 ve tedavisinde alt\u0131n standart kabul edilen Galyum-68 (Ga-68) PSMA PET\/BT G\u00f6r\u00fcnt\u00fcleme ve Lutesyum-177 (Lu-177) PSMA tedavisi Yak\u0131n Do\u011fu \u00dcniversitesi Hastanesi N\u00fckleer T\u0131p Anabilim Dal\u0131\u2019nda yak\u0131n bir zamanda uygulanmaya ba\u015fl\u0131yor. \u00c7ok erken evrede te\u015fhisin m\u00fcmk\u00fcn olaca\u011f\u0131 bu uygulama ile hastal\u0131k kontrol alt\u0131na al\u0131nabilecek. Di\u011fer tedavilerin cevap vermedi\u011fi ileri evre hastalar i\u00e7in de umut olacak.<\/p>\n
Yak\u0131n Do\u011fu \u00dcniversitesi Hastanesi N\u00fckleer T\u0131p Anabilim Dal\u0131 uzmanlar\u0131 Prof. Dr. F. Suna K\u0131ra\u00e7 ve Dr. \u00d6\u011fr. \u00dcyesi Deniz Bedel taraf\u0131ndan yap\u0131lan a\u00e7\u0131klamada, her ge\u00e7en g\u00fcn yeni geli\u015fmeler kaydedilen kanser hastal\u0131klar\u0131n\u0131n tan\u0131 ve tedavisinde, al\u0131nan \u00f6nlemler ve t\u0131p alan\u0131ndaki teknolojik yeniliklerin y\u00fcz g\u00fcld\u00fcr\u00fcc\u00fc sonu\u00e7lar\u0131n elde edilmesine olanak sa\u011flad\u0131\u011f\u0131, bunlardan birinin de d\u00fcnyada bir s\u00fcredir prostat kanserlerinin tan\u0131s\u0131nda alt\u0131n standart kabul edilen Ga-68 PSMA (Prostat spesifik membran antijeni) PET\/BT g\u00f6r\u00fcnt\u00fcleme ve t\u00fcm\u00f6r h\u00fccrelerinin yok edilmesini sa\u011flayacak Lu-177 PSMA tedavisi oldu\u011fu kaydedildi.<\/p>\n
Yak\u0131n Do\u011fu \u00dcniversitesi Hastanesi N\u00fckleer T\u0131p Anabilim Dal\u0131\u2019nda prostat kanseri tan\u0131 ve tedavisinde Ga-68 PSMA ve Lu-177 PSMA uygulamalar\u0131 i\u00e7in gerekli teknolojik donan\u0131m altyap\u0131s\u0131n\u0131n (radyofarmas\u00f6tik sentez \u00fcntesi) yak\u0131nda kurulaca\u011f\u0131 ifade edilen a\u00e7\u0131klamada, yak\u0131n zamanda Yak\u0131n Do\u011fu \u00dcniversitesi Hastanesi Kanser Merkezi \u00e7at\u0131s\u0131 alt\u0131nda bu alanda da hizmet verilmeye ba\u015flanaca\u011f\u0131 bildirildi.<\/p>\n
Prof. Dr. F. Suna K\u0131ra\u00e7: \u201cT\u00fcm\u00f6rl\u00fc dokular y\u00fczde 90\u2019n\u0131n \u00fczerinde do\u011frulukla saptanabiliyor”<\/p>\n
Son y\u0131llarda Ga-68 PSMA PET\/BT g\u00f6r\u00fcnt\u00fcleme y\u00f6nteminin prostat kanserlerinin tan\u0131, evreleme yani hastal\u0131\u011f\u0131n yayg\u0131nl\u0131k derecesinin saptanmas\u0131, tedavi planlamas\u0131 ve tedavi ba\u015far\u0131s\u0131n\u0131n de\u011ferlendirilmesinde g\u00fcvenli bir \u015fekilde kullan\u0131ld\u0131\u011f\u0131n\u0131 ifade eden Prof. Dr. F. Suna K\u0131ra\u00e7, kanser tan\u0131s\u0131nda kullan\u0131lan ak\u0131ll\u0131 molek\u00fcllerin, prostat kanseri h\u00fccrelerinin b\u00fcy\u00fck \u00e7o\u011funlu\u011funun y\u00fczeyinde bulunan PSMA gibi ba\u011flay\u0131c\u0131 yap\u0131 ta\u015flar\u0131na ba\u011flanmas\u0131 ile t\u00fcm\u00f6r h\u00fccrelerinin g\u00f6r\u00fcnt\u00fclenmesinin ve tedavisinin m\u00fcmk\u00fcn k\u0131l\u0131nd\u0131\u011f\u0131n\u0131 belirtti.<\/p>\n
Prostat kanseri tan\u0131s\u0131 konmu\u015f hastalara damar yolu ile Ga-68 PSMA uyguland\u0131ktan sonra di\u011fer kanser t\u00fcrlerinin tan\u0131 ve tedavi s\u00fcrecinde uygulanan PET\/BT g\u00f6r\u00fcnt\u00fcleme i\u015flemine benzer \u015fekilde PET\/BT t\u00fcm v\u00fccut taramas\u0131n\u0131n yap\u0131ld\u0131\u011f\u0131n\u0131 ifade eden K\u0131ra\u00e7, b\u00f6ylece minimum d\u00fczeydeki PSA (prostat spesifik antijen) y\u00fcksekliklerinde bile t\u00fcm\u00f6rl\u00fc dokular\u0131n ve metastazlar\u0131n\u0131n y\u00fczde 90\u2019n\u0131n \u00fczerinde do\u011frulukla tespit edilebildi\u011fini; b\u00f6ylece i\u015flemin hastal\u0131\u011f\u0131n evresi ve tedavi yakla\u015f\u0131m\u0131 konusunda hekime yol g\u00f6sterdi\u011fini kaydetti.<\/p>\n
Dr. \u00d6\u011fr. \u00dcyesi Deniz Bedel: \u201cGa-68 PSMA PET\/BT di\u011fer t\u00fcm tan\u0131 y\u00f6ntemlerinden \u00e7ok daha ba\u015far\u0131l\u0131\u201d<\/p>\n
Prostat kanserinin s\u0131kl\u0131kla yay\u0131l\u0131m g\u00f6sterdi\u011fi organa yak\u0131n lenf bezleri ve kemik gibi dokulardaki hastal\u0131\u011f\u0131n varl\u0131\u011f\u0131n\u0131 ortaya koyarak, hastaya yarar\u0131 olmayan ve \u00f6nemli yan etkileri beraberinde getiren tedavilerin bu y\u00f6ntemle \u00f6nlenebildi\u011fini belirten N\u00fckleer T\u0131p Anabilim Dal\u0131 Uzman\u0131 Dr. \u00d6\u011fr. \u00dcyesi Deniz Bedel, tedavi sonras\u0131 takipte ise hastal\u0131\u011f\u0131n n\u00fcks edip etmedi\u011finin, muayene bulgular\u0131, kan PSA de\u011ferleri veya ultrason, bilgisayarl\u0131 tomografi, manyetik rezonans g\u00f6r\u00fcnt\u00fcleme (MR) gibi y\u00f6ntemlerle ara\u015ft\u0131r\u0131labildi\u011fini ancak Ga-68 PSMA PET\/BT y\u00f6nteminin bu y\u00f6ntemlerin hepsinden \u00e7ok daha ba\u015far\u0131l\u0131 ve g\u00fcvenilir sonu\u00e7lar verdi\u011fini kaydetti.<\/p>\n
\u201c\u0130leri evre prostat kanseri vakalar\u0131nda ba\u015far\u0131l\u0131 sonu\u00e7lar al\u0131n\u0131yor\u201d<\/p>\n
\u201cGa-68 PSMA ile saptanan prostat kanser h\u00fccreleri, Lu-177 PSMA uygulanarak ba\u015far\u0131 ile tedavi edilebilmekte, bu hedefe y\u00f6nelik tedavi ile hastan\u0131n ya\u015fam s\u00fcresi ve kalitesi artt\u0131r\u0131labilmektedir\u201d diyen Bedel, Lu-177 PSMA tedavisinin \u00f6zellikle metastatik prostat kanseri olan hastalarda her ge\u00e7en g\u00fcn kullan\u0131m\u0131 artan bir y\u00f6ntem oldu\u011funu belirtti. Bu tedavinin t\u00fcm\u00f6r\u00fc k\u00fc\u00e7\u00fcltmeyi, yay\u0131l\u0131m\u0131n\u0131 durdurmay\u0131 ve hastal\u0131\u011f\u0131n neden oldu\u011fu kemik a\u011fr\u0131s\u0131 \u015fikayetlerini azaltmay\u0131 hedefledi\u011fini bildiren Bedel, Lu-177 PSMA tedavisinin, \u00e7o\u011funlukla di\u011fer tedavilere cevap al\u0131namayan hastalarda ve ileri evre prostat kanseri vak\u2019alar\u0131nda kullan\u0131ld\u0131\u011f\u0131n\u0131 ve hastal\u0131\u011f\u0131n uzun s\u00fcre kontrol alt\u0131nda tutulmas\u0131na katk\u0131 sa\u011flad\u0131\u011f\u0131n\u0131 da a\u00e7\u0131klad\u0131.<\/p>\n
Prostat kanseri belirtileri<\/p>\n
Prostat kanserinin belirtilerini de aktaran Bedel, \u201cErken evrede genellikle hi\u00e7bir belirti vermeyen prostat kanserlerinin ilerleyen evrelerinde ise, yava\u015f ya da zay\u0131f idrar ak\u0131m\u0131 veya daha s\u0131k idrara \u00e7\u0131kma ihtiyac\u0131, idrarda kan, ereksiyon sorunu (iktidars\u0131zl\u0131k), kemik metastazlar\u0131na ba\u011fl\u0131 kal\u00e7a, s\u0131rt, g\u00f6\u011f\u00fcs ya da di\u011fer alanlarda a\u011fr\u0131 \u015fikayetleri, bacak veya ayaklarda uyu\u015fma veya g\u00fc\u00e7s\u00fczl\u00fck, omurilik bas\u0131s\u0131na ba\u011fl\u0131 mesane veya ba\u011f\u0131rsak kontrol\u00fc kayb\u0131 g\u00f6zlenmektedir. Bir\u00e7ok ba\u015fka hastal\u0131\u011f\u0131n habercisi de olabilecek bu belirtilerin bulunmas\u0131 durumunda mutlaka bir uzmana ba\u015fvurulmal\u0131\u201d dedi.<\/p>\n","protected":false},"excerpt":{"rendered":"
50 YA\u015e \u00dcZER\u0130 ERKEKLERDE EN SIK G\u00d6R\u00dcLEN T\u00dcR OLAN PROSTAT KANSER\u0130N\u0130N TANI VE TEDAV\u0130S\u0130NDE ALTIN STANDART KABUL ED\u0130LEN GALYUM-68 (GA-68) PSMA PET\/BT G\u00d6R\u00dcNT\u00dcLEME VE LUTESYUM-177 (LU-177) PSMA TEDAV\u0130S\u0130 YAKIN DO\u011eU \u00dcN\u0130VERS\u0130TES\u0130 HASTANES\u0130 N\u00dcKLEER TIP ANAB\u0130L\u0130M DALI\u2019NDA YAKIN B\u0130R ZAMANDA UYGULANMAYA BA\u015eLIYOR. \u00c7OK ERKEN EVREDE TE\u015eH\u0130S\u0130N M\u00dcMK\u00dcN OLACA\u011eI BU UYGULAMA \u0130LE HASTALIK KONTROL ALTINA ALINAB\u0130LECEK. D\u0130\u011eER TEDAV\u0130LER\u0130N CEVAP VERMED\u0130\u011e\u0130 \u0130LER\u0130 EVRE HASTALAR \u0130\u00c7\u0130N DE UMUT OLACAK.<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[1],"tags":[16758,18871,2747,42363,5459,42364,87],"class_list":["post-174324","post","type-post","status-publish","format-standard","hentry","category-genel","tag-prostat","tag-kanserine","tag-kolaylasiyor","tag-koymak","tag-tani","tag-uygulamalarla","tag-yeni"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/paKIfm-JlG","_links":{"self":[{"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/posts\/174324","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/comments?post=174324"}],"version-history":[{"count":0,"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/posts\/174324\/revisions"}],"wp:attachment":[{"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/media?parent=174324"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/categories?post=174324"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/tags?post=174324"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}