Anadolu \u00dcniversitesi ve Eski\u015fehir Teknik \u00dcniversitesi \u00f6\u011fretim \u00fcyeleri, ortakla\u015fa y\u00fcr\u00fctt\u00fckleri \u00e7al\u0131\u015fmalarla bilim d\u00fcnyas\u0131na katk\u0131da bulunmaya devam ediyor.<\/p>\n
Bu kapsamda son olarak Anadolu \u00dcniversitesi A\u00e7\u0131k\u00f6\u011fretim Fak\u00fcltesi Sa\u011fl\u0131k Programlar\u0131 Ba\u015fkan\u0131 Do\u00e7. Dr. G\u00f6khan Ku\u015f ile Eski\u015fehir Teknik \u00dcniversitesi Fen Fak\u00fcltesi Biyoloji B\u00f6l\u00fcm\u00fc \u00d6\u011fretim \u00dcyesi Prof. Dr. Mehtap Kutlu\u2019nun birlikte hayata ge\u00e7irdikleri, \u201cCeranib-2 Kullan\u0131m\u0131 ile Akci\u011fer Kanserinin Tedavisi\u201d bulu\u015fu, Amerika Birle\u015fik Devletleri (ABD) Patent ve Marka Ofisi\u2019nden patent ald\u0131. T\u00fcrkiye ve \u00fcniversitemiz ad\u0131na bir ilk olma \u00f6zelli\u011fi ta\u015f\u0131yan bu patent ile yerli ve milli bir kanser ilac\u0131 geli\u015ftirilmesi ama\u00e7lan\u0131yor. Anadolu \u00dcniversitesi ile Eski\u015fehir Teknik \u00dcniversitesi ortakl\u0131\u011f\u0131nda tamamlanarak patentlenen proje, akci\u011fer kanseri h\u00fccrelerinde bir enzim olan \u201cSeramidaz\u201d\u0131n inhibit\u00f6r\u00fc \u201cCeranib-2\u201dnin bu kanser t\u00fcr\u00fcnde ba\u015far\u0131l\u0131 sonu\u00e7lar al\u0131nd\u0131\u011f\u0131 ve maddenin kullan\u0131labilir oldu\u011fu sonucunu da ortaya \u00e7\u0131kard\u0131.<\/p>\n
Prof. Dr. Kutlu ve Do\u00e7. Dr. Ku\u015f: \u201cAkci\u011fer kanseri h\u00fccrelerini \u00f6l\u00fcme g\u00f6t\u00fcrmeyi ba\u015fard\u0131k\u201d<\/p>\n
Prof. Dr. Mehtap Kutlu ve Do\u00e7. Dr. G\u00f6khan Ku\u015f, bilim d\u00fcnyas\u0131 ad\u0131na bir ilk olma \u00f6zelli\u011fi ta\u015f\u0131yan projenin detaylar\u0131na ili\u015fkin a\u00e7\u0131klamalarda bulundu. Kanser \u00e7al\u0131\u015fmalar\u0131n\u0131n son zamanlarda artm\u0131\u015f olmas\u0131na ra\u011fmen kanser vakalar\u0131n\u0131n da her t\u00fcrl\u00fc tedaviye ra\u011fmen h\u0131zl\u0131 bir art\u0131\u015f g\u00f6sterdi\u011fine dikkat \u00e7eken Prof. Dr. Mehtap Kutlu ve Do\u00e7. Dr. G\u00f6khan Ku\u015f, g\u00f6r\u00fc\u015flerini \u015fu \u015fekilde aktard\u0131lar:<\/p>\n
\u201cKanser olu\u015fumu ve geli\u015fimi ile ilgili olarak \u00e7ok say\u0131da biyolojik mekanizma bulunuyor. Biyolojik olarak aktif lipitlerin kanserin tan\u0131, te\u015fhis ve tedavisindeki rolleri olduk\u00e7a b\u00fcy\u00fck. Lipit metabolizmas\u0131ndaki yollarda ise pek \u00e7ok enzim yol almaktad\u0131r. Biz de bu enzimlerden \u2018seramidaz\u2019 enziminin \u00e7al\u0131\u015fmas\u0131n\u0131 bask\u0131layarak akci\u011fer kanseri h\u00fccrelerini \u00f6l\u00fcme g\u00f6t\u00fcrmeyi ba\u015fard\u0131k.\u201d<\/p>\n
\u201c\u00dclkemiz i\u00e7in yerli ve milli bir kanser ilac\u0131 geli\u015ftirme amac\u0131nday\u0131z\u201d<\/p>\n
Projenin ilerleyen s\u00fcre\u00e7lerdeki ama\u00e7lar\u0131na da de\u011finen Prof. Dr. Kutlu ve Do\u00e7. Dr. Ku\u015f, \u015fu bilgileri aktard\u0131lar:<\/p>\n
\u201cBundan sonras\u0131 i\u00e7in bu ve di\u011fer bile\u015fikler ile ilgili nano form\u00fclasyona ait pek \u00e7ok patent ba\u015fvurumuz bulunuyor. Ancak bunlar\u0131n geli\u015ftirilip preklinik a\u015famaya ge\u00e7ebilmesi i\u00e7in in vivo de\u011ferlerine ihtiyac\u0131m\u0131z var. Biyokimyasal ve molek\u00fcler teknikler ile lipidomiks baz\u0131nda verilen desteklerle de bulu\u015flar\u0131m\u0131z geli\u015ftirilecek. \u00d6n\u00fcm\u00fczdeki 5 sene i\u00e7erisinde kanserin her alan\u0131nda \u00fclkemiz i\u00e7in yerli, milli ve s\u0131f\u0131rdan bir kanser ilac\u0131 geli\u015ftirebilmeyi ama\u00e7l\u0131yoruz.\u201d<\/p>\n
Prof. Dr. Mehtap Kutlu ve Do\u00e7. Dr. G\u00f6khan Ku\u015f, elde ettikleri bu b\u00fcy\u00fck ba\u015far\u0131yla ilgili son olarak \u015funlar\u0131 ifade ettiler:<\/p>\n
\u201c\u00c7al\u0131\u015fmalar\u0131m\u0131z sonucunda elde etti\u011fimiz bulgular\u0131n uluslararas\u0131 bir patent ile sonu\u00e7lanmas\u0131 bizleri olduk\u00e7a mutlu etti. Patent ba\u015fvuru ve patent al\u0131m s\u00fcre\u00e7leri olduk\u00e7a yorucu ve uzun s\u00fcrd\u00fc. Tabii ki bu i\u015fin bir de maddi boyutlar\u0131 var. Bu s\u00fcre\u00e7te t\u00fcm bu s\u0131k\u0131nt\u0131lar\u0131n a\u015f\u0131lmas\u0131nda bize destek veren ba\u015fta Anadolu \u00dcniversitesine olmak \u00fczere \u00dcniversitemiz Ar-Ge ve \u0130novasyon Koordinasyon Birimine (AR\u0130NKOM) ve projemizde g\u00f6rev alan \u00f6\u011frencilerimize \u00e7ok te\u015fekk\u00fcr ederiz.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"
ANADOLU \u00dcN\u0130VERS\u0130TES\u0130 A\u00c7IK\u00d6\u011eRET\u0130M FAK\u00dcLTES\u0130 SA\u011eLIK PROGRAMLARI BA\u015eKANI DO\u00c7. DR. G\u00d6KHAN KU\u015e \u0130LE ESK\u0130\u015eEH\u0130R TEKN\u0130K \u00dcN\u0130VERS\u0130TES\u0130 FEN FAK\u00dcLTES\u0130 B\u0130YOLOJ\u0130 B\u00d6L\u00dcM\u00dc \u00d6\u011eRET\u0130M \u00dcYES\u0130 PROF. DR. MEHTAP KUTLU\u2019NUN B\u0130RL\u0130KTE HAYATA GE\u00c7\u0130RD\u0130KLER\u0130, \u201cCERAN\u0130B-2 KULLANIMI \u0130LE AKC\u0130\u011eER KANSER\u0130N\u0130N TEDAV\u0130S\u0130\u201d BULU\u015eU, AMER\u0130KA B\u0130RLE\u015e\u0130K DEVLETLER\u0130 PATENT VE MARKA OF\u0130S\u0130\u2019NDEN PATENT ALDI. \u00dcLKEM\u0130Z VE \u00dcN\u0130VERS\u0130TEM\u0130Z ADINA B\u0130R \u0130LK OLMA \u00d6ZELL\u0130\u011e\u0130 TA\u015eIYAN BU PATENT \u0130LE YERL\u0130 VE M\u0130LL\u0130 B\u0130R KANSER \u0130LACI GEL\u0130\u015eT\u0130R\u0130LMES\u0130 AMA\u00c7LANIYOR.<\/p>\n","protected":false},"author":1,"featured_media":200202,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[1],"tags":[7429,17542,350,429,332,10119,2454,1464],"class_list":["post-200201","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-genel","tag-adim","tag-ilaci","tag-kanser","tag-milli","tag-onemli","tag-patent","tag-yerli","tag-yolunda"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"https:\/\/i0.wp.com\/www.tvturk.com\/wp-content\/uploads\/2019\/09\/yerli-ve-milli-kanser-ilaci-yolunda-onemli-adim-us-patent_b20817b.jpg?fit=841%2C464","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/paKIfm-Q53","_links":{"self":[{"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/posts\/200201","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/comments?post=200201"}],"version-history":[{"count":0,"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/posts\/200201\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/media\/200202"}],"wp:attachment":[{"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/media?parent=200201"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/categories?post=200201"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/tags?post=200201"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}