Cumhurba\u015fkanl\u0131\u011f\u0131 K\u00fclliyesi\u2019nde Cumhurba\u015fkan\u0131 Recep Tayyip Erdo\u011fan taraf\u0131ndan \u2018Y\u00d6K 2019 \u00dcst\u00fcn Ba\u015far\u0131 \u00d6d\u00fclleri\u2019 kapsam\u0131nda \u00f6d\u00fcl alan S\u00fcleyman Demirel \u00dcniversitesi (SD\u00dc) Eczac\u0131l\u0131k Fak\u00fcltesi Biyokimya Anabilimdal\u0131 Dr. \u00d6\u011fretim \u00dcyesi Yal\u00e7\u0131n Erzurumlu gazetecilere yapt\u0131\u011f\u0131 a\u00e7\u0131klamada, \u201cCumhurba\u015fkan\u0131ndan b\u00f6yle bir \u00f6d\u00fcl almak \u00e7ok g\u00fczel. Cumhurba\u015fkan\u0131m\u0131z o toplant\u0131da \u00fcniversitedeki e\u011fitim kurumlar\u0131m\u0131zdan akademik \u00e7al\u0131\u015fmalar\u0131na daha h\u0131zl\u0131 ve daha verimli bir \u015fekilde y\u00f6nelmelerini rica etti. Biz de elimizden geldi\u011fince, vatan\u0131m\u0131za ve milletimize yararl\u0131 \u00f6\u011frenciler yeti\u015ftirmeye \u00e7al\u0131\u015f\u0131yoruz. \u00d6d\u00fcl\u00fc ald\u0131k ancak bizim sorumluluklar\u0131m\u0131z b\u00f6ylelikle daha da b\u00fcy\u00fcd\u00fc, bu \u00e7al\u0131\u015fmalar\u0131 daha da ileriye ta\u015f\u0131mak bizim boynumuzun borcu ve belki de prostat kanserinin tedavisine y\u00f6nelik daha fonksiyonel tedavilerin ortaya konulmas\u0131na arac\u0131l\u0131k etmek bizim borcumuz\u201d ifadelerini kulland\u0131.<\/p>\n
Cumhurba\u015fkanl\u0131\u011f\u0131 K\u00fclliyesi\u2019nde d\u00fczenlenen Akademik Y\u0131l A\u00e7\u0131l\u0131\u015f\u0131\u2019nda, \u2018Prostat Kanserinde Yeni H\u00fccresel Bir Mekanizman\u0131n Ayd\u0131nlat\u0131lmas\u0131\u2019 alan\u0131nda yapt\u0131\u011f\u0131 doktora teziyle SD\u00dc Eczac\u0131l\u0131k Fak\u00fcltesi\u2019nden Dr. \u00d6\u011fretim \u00dcyesi Yal\u00e7\u0131n Erzurumlu, \u2018Y\u00d6K 2019 \u00dcst\u00fcn Ba\u015far\u0131 \u00d6d\u00fclleri\u2019 kapsam\u0131nda Cumhurba\u015fkan\u0131 Recep Tayyip Erdo\u011fan taraf\u0131ndan \u00f6d\u00fcllendirildi.<\/p>\n
D\u00fcnya \u00e7ap\u0131nda, literat\u00fcrde ilk kez tamamen yerli ve milli \u00e7al\u0131\u015fmalarla T\u00fcrk bilim insanlar\u0131n\u0131n ortaya koydu\u011fu \u00e7al\u0131\u015fma ile prostat kanserindeki olas\u0131 potansiyel rol\u00fc ortaya \u00e7\u0131kar\u0131ld\u0131. Yap\u0131lan \u00e7al\u0131\u015fma kapsam\u0131nda, bu mekanizman\u0131n, testosteronlar arac\u0131l\u0131\u011f\u0131 ile nas\u0131l kontrol ve regile edildi\u011fini ortaya koyduklar\u0131n\u0131 aktaran SD\u00dc Eczac\u0131l\u0131k Fak\u00fcltesi Biyokimya Anabilimdal\u0131 Dr. \u00d6\u011fretim \u00dcyesi Yal\u00e7\u0131n Erzurumlu, \u201cLiterat\u00fcrde ilk kez bu mekanizman\u0131n hormon arac\u0131l\u0131\u011f\u0131yla, \u00f6zellikle testosteronlar arac\u0131l\u0131\u011f\u0131yla nas\u0131l regile oldu\u011funu ortaya koyan bir \u00e7al\u0131\u015fma yapt\u0131k ve bunu karakterize ettik\u201d dedi.<\/p>\n
G\u00f6rev yapt\u0131\u011f\u0131 fak\u00fcltede \u00f6d\u00fcl ald\u0131ktan sonra gazetecilere a\u00e7\u0131klamalarda bulunan Yal\u00e7\u0131n Erzurumlu, \u00f6d\u00fcl ald\u0131\u011f\u0131 \u00e7al\u0131\u015fmay\u0131 \u015f\u00f6yle \u00f6zetledi:<\/p>\n
\u201cYakla\u015f\u0131k 1 y\u0131l \u00f6nce Ege \u00dcniversitesi Eczac\u0131l\u0131k Fak\u00fcltesi\u2019ndeki Biyokimya B\u00f6l\u00fcm\u00fc\u2019nde doktora e\u011fitimimi ve \u00f6ncesinde y\u00fcksek lisans\u0131m\u0131 tamamlad\u0131ktan sonra buraya geldim, akademik faaliyetlerimi art\u0131k burada s\u00fcrd\u00fcrece\u011fim. Biz, Ege \u00dcniversitesi\u2019ndeki Eczac\u0131l\u0131k Fak\u00fcltesi Laboratuvar\u0131\u2019nda uzun y\u0131llar boyunca ubikitin-proteazom sistemi ad\u0131 verilen bir konu \u00fczerine \u00e7al\u0131\u015fmalar\u0131m\u0131z\u0131 s\u00fcrd\u00fcrd\u00fck. Ubikitin-proteazom sistemini, asl\u0131nda h\u00fccrelerin kontrol sistemi kontrol mekanizmas\u0131 olarak ifade edebiliriz. Bir h\u00fccreyi normal \u015fartlarda inceledi\u011finizde, d\u00fczenli olarak bir yap\u0131m – y\u0131k\u0131m i\u015flevi s\u00f6z konusu. Bu yap\u0131m ve y\u0131k\u0131m i\u015flerinin birbiriyle dengeli \u015fekilde ilerlemesi son derece \u00f6nemli. Ancak, bu s\u00fcrecin ilerlemesinde, \u00f6zellikle kalite – kontrol mekanizmalar\u0131, yani bunu g\u00fcnl\u00fck hayattaki bir fabrikaya benzetebiliriz. S\u00fcrekli bir hammadde giri\u015fi var, bu hammadde girdikten sonra fabrikada bir \u00fcr\u00fcn olarak d\u0131\u015far\u0131ya \u00e7\u0131k\u0131yor. Bu \u00e7\u0131kan \u00fcr\u00fcnlerin birileri taraf\u0131ndan denetlenmesi ve uygun standartlarda fabrikadan d\u0131\u015far\u0131ya, kullan\u0131c\u0131ya sunulmas\u0131 gerekiyor. H\u00fccrelerdeki i\u015fleyi\u015f de tamamen bundan ibaret. Ubikitin-proteazom sistemi bu noktada, bu fabrikalar\u0131n kalite – kontrol mekanizmas\u0131 olarak i\u015f g\u00f6r\u00fcyor. Bizim \u00e7al\u0131\u015ft\u0131\u011f\u0131m\u0131z konu, ERAD (ER-associated degradation) ad\u0131 verilen ER arac\u0131l\u0131\u011f\u0131yla protein y\u0131k\u0131m yolu veya ER arac\u0131l\u0131\u011f\u0131yla y\u0131k\u0131m olarak da ifade edilen bu mekanizma, bu h\u00fccre i\u00e7erisinde, bizim protein olarak ifade etti\u011fimiz biyomolek\u00fcllerin, uygun formda, uygun konformasyonda, \u00f6zellikle ER i\u00e7erisinde, endoplazmik retikulum ile ili\u015fkili, sentezlenen proteinlerin kalite kontrol\u00fcn\u00fc ger\u00e7ekle\u015ftiren ve ger\u00e7ekten uygun standartlarda olan proteinlerin h\u00fccrenin endoplazmik retikulumundan stoplazmas\u0131na ge\u00e7i\u015fini kontrol eden, oradan da h\u00fccrenin d\u0131\u015far\u0131s\u0131na aktar\u0131lmas\u0131n\u0131 denetleyen bir mekanizma olarak kar\u015f\u0131m\u0131za \u00e7\u0131k\u0131yor. Asl\u0131nda biz tam olarak \u015funu yapt\u0131k. Biz, uzun y\u0131llard\u0131r mekanizmay\u0131 \u00e7al\u0131\u015f\u0131yoruz. Elbette ki mekanizman\u0131n bilinen bir\u00e7ok noktas\u0131 var. Mekanizmayla alakal\u0131 hala ayd\u0131nlat\u0131lmam\u0131\u015f bir\u00e7ok nokta da s\u00f6z konusu. Biz, bu mekanizman\u0131n prostat kanserindeki olas\u0131 potansiyel rol\u00fcn\u00fc ortaya koyduk ve ayn\u0131 zamanda yine prostat kanserinde testosteron d\u00fczeylerinin olduk\u00e7a \u00f6nemli oldu\u011funu hepimiz biliyoruz. Bu mekanizman\u0131n, testosteronlar arac\u0131l\u0131\u011f\u0131 ile nas\u0131l kontrol edildi\u011fini ve regile edildi\u011fini ortaya koyan bir \u00e7al\u0131\u015fma yapt\u0131k. Literat\u00fcrde ilk kez bu mekanizman\u0131n hormon arac\u0131l\u0131\u011f\u0131yla, \u00f6zellikle testosteronlar arac\u0131l\u0131\u011f\u0131yla nas\u0131l regile oldu\u011funu ortaya koyan bir \u00e7al\u0131\u015fma yapt\u0131k ve bunu karakterize ettik. Bunu da d\u00fcnyan\u0131n en sayg\u0131n dergilerinden bir tanesi olan NATURE, Scientific Reports\u2019ta yay\u0131nlad\u0131k\u201d.<\/p>\n
Yerli ve milli \u00e7al\u0131\u015fmay\u0131 d\u00fcnya ilk kez literat\u00fcr\u00fcne soktular<\/p>\n
\u201cBu \u00e7al\u0131\u015fman\u0131n \u00f6nemli bir noktas\u0131, literat\u00fcre \u00f6nemli bir veri kazand\u0131rmas\u0131n\u0131n yan\u0131 s\u0131ra, tamamen \u00fclkemizde yap\u0131lm\u0131\u015f olmas\u0131 bizim i\u00e7in olduk\u00e7a \u00f6nemliydi\u201d diyerek s\u00f6zlerini s\u00fcrd\u00fcren Erzurumlu, \u201cBu anlamda Prof. Dr. Petek Ballar ile birlikte uzun mesai saatleri harcad\u0131k. Tabii ki bu bir ekip i\u015fidir. Aziz Sancar\u2019\u0131n da dedi\u011fi gibi, \u2018Bilimde liyakat \u00e7ok \u00f6nemlidir.\u2019 Biz, \u2018bir hocan\u0131n bir \u00f6\u011frencisine el vermesi\u2019 olarak da bu durumu ifade edebiliriz. Desteklemesi, onu e\u011fitmesi olduk\u00e7a \u00f6nemlidir. Zannediyorum, Prof. Dr. Ballar ile birlikte biz bu s\u00fcreci iyi y\u00f6nettik. Kendisi \u00e7ok k\u0131ymetli ve \u00f6nemli bir ment\u00f6rd\u00fcr, ben de elimden geldi\u011fince iyi bir \u00f6\u011frenci olmaya \u00e7al\u0131\u015ft\u0131m. Bu anlamda, bu yolda elimden geldi\u011fince kendimi geli\u015ftirmeye \u00e7al\u0131\u015ft\u0131m, bilim camias\u0131na \u00f6nemli katk\u0131lar sa\u011flamaya \u00e7al\u0131\u015ft\u0131k\u201d \u015feklinde konu\u015ftu.<\/p>\n
\u201c\u00d6d\u00fcl\u00fc ald\u0131k, ancak bizim sorumluluklar\u0131m\u0131z b\u00f6ylelikle daha da b\u00fcy\u00fcd\u00fc\u201d<\/p>\n
\u201cCumhurba\u015fkan\u0131\u2019ndan b\u00f6yle bir \u00f6d\u00fcl almak \u00e7ok g\u00fczel\u201d \u015feklinde s\u00f6zlerini s\u00fcrd\u00fcren Dr. \u00d6\u011fretim \u00dcyesi Erzurumlu, \u015f\u00f6yle konu\u015ftu:<\/p>\n
\u201cHepimiz \u00e7ok heyecanl\u0131yd\u0131k, Cumhurba\u015fkanl\u0131\u011f\u0131 K\u00fcllyesi\u2019nde ilk defa bulundum. Orada olmak, o atmosferi tatmak olduk\u00e7a \u00f6nemliydi. Akademik y\u0131l a\u00e7\u0131l\u0131\u015f toplant\u0131s\u0131yd\u0131. \u00dclkemizdeki t\u00fcm rekt\u00f6rler ve rekt\u00f6r yard\u0131mc\u0131lar\u0131 oradayd\u0131. Cumhurba\u015fkan\u0131m\u0131z, o toplant\u0131da \u00fcniversitedeki e\u011fitim kurumlar\u0131m\u0131zdan akademik \u00e7al\u0131\u015fmalar\u0131na daha h\u0131zl\u0131 ve daha verimli bir \u015fekilde y\u00f6nelmelerini rica etti. Biz de elimizden geldi\u011fince vatan\u0131m\u0131za ve milletimize yararl\u0131 \u00f6\u011frenciler yeti\u015ftirmeye \u00e7al\u0131\u015f\u0131yoruz. \u00d6d\u00fcl\u00fc ald\u0131k ancak bizim sorumluluklar\u0131m\u0131z b\u00f6ylelikle daha da b\u00fcy\u00fcd\u00fc, bu \u00e7al\u0131\u015fmalar\u0131 daha da ileriye ta\u015f\u0131mak bizim boynumuzun borcu ve belki de prostat kanserinin tedavisine y\u00f6nelik daha fonksiyonel tedavilerin ortaya konulmas\u0131na arac\u0131l\u0131k etmek bizim borcumuz.\u201d<\/p>\n
\u201cElimizden gelenin en iyisini yapmakta, b\u00fcy\u00fck bir gayretle \u00e7al\u0131\u015fmalar\u0131m\u0131z\u0131 s\u00fcrd\u00fcrece\u011fiz\u201d<\/p>\n
Erzurumlu ayr\u0131ca, T\u00fcrkiye\u2019de bilimsel \u00e7al\u0131\u015fmalar i\u00e7in gereken b\u00fct\u00e7e s\u0131k\u0131nt\u0131lar\u0131ndan bahsederek, \u201c\u00dclkemizde bilimsel \u00e7al\u0131\u015fmalar\u0131 y\u00fcr\u00fctmek ger\u00e7ekten zor. \u00dclkemizin b\u00fcy\u00fck kurumlar\u0131 bu faaliyetlerin s\u00fcrd\u00fcr\u00fclmesinde b\u00fcy\u00fck b\u00fct\u00e7eler sunuyorlar. \u00d6zellikle T\u00dcB\u0130TAK, Y\u00d6K, ancak \u00e7o\u011fu zaman bir s\u00fcr\u00fc akademisyen akademik faaliyetlerini s\u00fcrd\u00fcrmekte zorlan\u0131yor. \u00c7\u00fcnk\u00fc, bir tak\u0131m b\u00fct\u00e7e yetersizlikleri s\u00f6z konusu olabiliyor. Bu anlamda, Y\u00d6K\u2019ten, Cumhurba\u015fkanl\u0131\u011f\u0131m\u0131zdan, \u00e7al\u0131\u015fmalar\u0131m\u0131z\u0131n desteklenmesi konusunda desteklerini zaten esirgemeyeceklerini zaten biliyoruz ve desteklerini bekliyoruz. Biz de, tabii ki bu ba\u011flamda elimizden gelenin en iyisini yapmakta, b\u00fcy\u00fck bir gayretle \u00e7al\u0131\u015fmalar\u0131m\u0131z\u0131 s\u00fcrd\u00fcrece\u011fiz\u201d ifadelerini kulland\u0131.<\/p>\n","protected":false},"excerpt":{"rendered":"
CUMHURBA\u015eKANLI\u011eI K\u00dcLL\u0130YES\u0130\u2019NDE CUMHURBA\u015eKANI RECEP ERDO\u011eAN TARAFINDAN \u2018Y\u00d6K 2019 \u00dcST\u00dcN BA\u015eARI \u00d6D\u00dcLLER\u0130\u2019 KAPSAMINDA \u00d6D\u00dcL ALAN S\u00dcLEYMAN DEM\u0130REL \u00dcN\u0130VERS\u0130TES\u0130 (SD\u00dc) ECZACILIK FAK\u00dcLTES\u0130 B\u0130YOK\u0130MYA ANAB\u0130L\u0130MDALI DR.\u00d6\u011eRET\u0130M \u00dcYES\u0130 ERZURUMLU GAZETEC\u0130LERE YAPTI\u011eI A\u00c7IKLAMADA, \u201cCUMHURBA\u015eKANINDAN B\u00d6YLE B\u0130R \u00d6D\u00dcL ALMAK \u00c7OK G\u00dcZEL. CUMHURBA\u015eKANIMIZ O TOPLANTIDA \u00dcN\u0130VERS\u0130TEDEK\u0130 E\u011e\u0130T\u0130M KURUMLARIMIZDAN AKADEM\u0130K \u00c7ALI\u015eMALARINA DAHA HIZLI VE DAHA VER\u0130ML\u0130 B\u0130R \u015eEK\u0130LDE Y\u00d6NELMELER\u0130N\u0130 R\u0130CA ETT\u0130. B\u0130Z DE EL\u0130M\u0130ZDEN GELD\u0130\u011e\u0130NCE, VATANIMIZA VE M\u0130LLET\u0130M\u0130ZE YARARLI \u00d6\u011eRENC\u0130LER YET\u0130\u015eT\u0130RMEYE \u00c7ALI\u015eIYORUZ. \u00d6D\u00dcL\u00dc ALDIK, ANCAK B\u0130Z\u0130M SORUMLUKLARIMIZ B\u00d6YLEL\u0130KLE DAHA DA B\u00dcY\u00dcD\u00dc, BU \u00c7ALI\u015eMALARI DAHA DA \u0130LER\u0130YE TA\u015eIMAK B\u0130Z\u0130M BOYNUMUZUN BORCU VE BELK\u0130 DE PROSTAT KANSER\u0130N\u0130N TEDAV\u0130S\u0130NE Y\u00d6NEL\u0130K DAHA FONKS\u0130YONEL TEDAV\u0130LER\u0130N ORTAYA KONULMASINA ARACILIK ETMEK B\u0130Z\u0130M BORCUMUZ\u201d \u0130FADELER\u0130N\u0130 KULLANDI.<\/p>\n","protected":false},"author":1,"featured_media":205461,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"jetpack_post_was_ever_published":false},"categories":[1],"tags":[1075,436,503,570,11926,1553,51877,22338,664],"class_list":["post-205460","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-genel","tag-aldi","tag-basari","tag-cumhurbaskani","tag-doktora","tag-erdogandan","tag-odulu","tag-teziyle","tag-ustun","tag-yok"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"https:\/\/i0.wp.com\/www.tvturk.com\/wp-content\/uploads\/2019\/09\/doktora-teziyle-cumhurbaskani-erdogandan-yok-ustun-basari-odulu-aldi_07e9ba5.jpg?fit=1000%2C666","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/paKIfm-RrS","_links":{"self":[{"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/posts\/205460","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/comments?post=205460"}],"version-history":[{"count":0,"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/posts\/205460\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/media\/205461"}],"wp:attachment":[{"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/media?parent=205460"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/categories?post=205460"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/tags?post=205460"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}