Ege \u00dcniversitesi (E\u00dc) Fen Fak\u00fcltesi \u00d6\u011fretim \u00dcyesi Prof. Dr. \u015eenay Hamarat \u015eanl\u0131er \u00f6nc\u00fcl\u00fc\u011f\u00fcnde geli\u015ftirilen proje kapsam\u0131nda, karaci\u011fer kanserinin tedavisinde sa\u011fl\u0131kl\u0131 h\u00fccrelere zarar vermeden hedefli ila\u00e7 tedavisi yap\u0131labilmesi amac\u0131yla \u00e7al\u0131\u015fma ba\u015flat\u0131ld\u0131\u011f\u0131 a\u00e7\u0131kland\u0131.<\/p>\n
Ege \u00dcniversitesi (E\u00dc) Fen Fak\u00fcltesi Biyokimya B\u00f6l\u00fcm\u00fc \u00d6\u011fretim \u00dcyesi, ayn\u0131 zamanda E\u00dc \u0130la\u00e7 Geli\u015ftirme ve Farmakokinetik Ara\u015ft\u0131rma-Uygulama Merkezi (ARGEFAR) M\u00fcd\u00fcr Yard\u0131mc\u0131s\u0131 Prof. Dr. \u015eenay Hamarat \u015eanl\u0131er, karaci\u011fer kanserinin tedavisine y\u00f6nelik yeni bir proje \u00fczerine \u00e7al\u0131\u015fma ba\u015flatt\u0131. Kansere kar\u015f\u0131 bilimle sava\u015f a\u00e7an Prof. Dr. \u015eanl\u0131er, ekibiyle karaci\u011fer kanserinin hedefli tedavisine y\u00f6nelik ila\u00e7 ta\u015f\u0131y\u0131c\u0131 sisteminin geli\u015ftirilmesi amac\u0131yla proje geli\u015ftirdi. Proje, T\u00fcrkiye Bilimsel ve Teknolojik Ara\u015ft\u0131rma Kurumu (T\u00dcB\u0130TAK) taraf\u0131ndan da kabul ald\u0131. Geli\u015ftirilen projeyle, karaci\u011fer kanserinin tedavisinde sa\u011fl\u0131kl\u0131 h\u00fccrelere zarar vermeden hedefli ila\u00e7 tedavisi yap\u0131labilece\u011fi kaydedildi.<\/p>\n
E\u00dc Rekt\u00f6r\u00fc Prof. Dr. Necdet Budak da, projeyle ilgili bilgi almak \u00fczere Prof. Dr. \u015eanl\u0131er\u2019i ziyaret etti. Projede, Dokuz Eyl\u00fcl, Adnan Menderes, Ekonomi ve Erzincan \u00fcniversitelerinden de akademisyenlerin g\u00f6rev ald\u0131\u011f\u0131n\u0131 dile getiren Rekt\u00f6r Budak, “\u015eenay hocam\u0131z ara\u015ft\u0131rma ekibi, \u00fcniversitemizin \u0130la\u00e7 Geli\u015ftirme ve Farmakokinetik Ara\u015ft\u0131rma-Uygulama Merkezinde bir proje geli\u015ftirdi. Bu proje, T\u00dcB\u0130TAK taraf\u0131ndan kabul edildi. Projenin amac\u0131; karaci\u011ferde kanser h\u00fccrelerine y\u00f6nelik olarak ila\u00e7 ta\u015f\u0131ma sisteminin geli\u015ftirilmesi. Bu, tamamen bireysel odakl\u0131 tedavi y\u00f6ntemi olacak ve T\u00dcB\u0130TAK taraf\u0131ndan da g\u00fc\u00e7l\u00fc bir \u015fekilde destekleniyor. Hocalar\u0131m\u0131z\u0131, \u00e7al\u0131\u015fmalar\u0131ndan dolay\u0131 tebrik ediyor, ba\u015far\u0131lar diliyorum. Ege \u00dcniversitesi Rekt\u00f6r\u00fc olarak, vatanda\u015flar\u0131m\u0131za umut olaca\u011f\u0131n\u0131 d\u00fc\u015f\u00fcnd\u00fc\u011f\u00fcm\u00fcz bu \u00e7al\u0131\u015fmalar\u0131n ba\u015far\u0131yla sonu\u00e7lanmas\u0131n\u0131 \u00fcmit ediyorum” diye konu\u015ftu.<\/p>\n
Tedavi s\u0131ras\u0131nda sa\u011fl\u0131kl\u0131 h\u00fccreler zarar g\u00f6rmeyecek<\/p>\n
Karaci\u011fer kanser tedavisinde, kanser lokalizasyonuna ve evrelerine ba\u011fl\u0131 olarak kemoterapi, transkateter terapi, radyoterapi ve ko\u015fullar\u0131n uygun olmas\u0131 durumunda organ nakli ger\u00e7ekle\u015ftirilebildi\u011fine dikkat \u00e7eken Prof. Dr. \u015eanl\u0131er, t\u00fcm\u00f6r\u00fcn boyutu, \u00e7ok odakl\u0131l\u0131k ve vask\u00fcler invazyon gibi fakt\u00f6rler nedeniyle karaci\u011fer hastalar\u0131n\u0131n sadece y\u00fczde 15\u2019inde cerrahi i\u015flem uygulanabildi\u011fini s\u00f6yledi. Projeyle ilgili bilgi veren Prof. Dr. \u015eanl\u0131er, “Proje kapsam\u0131nda, karaci\u011fer kanser tedavisinde geleneksel kemoterapide g\u00f6zlenen olumsuzluklar\u0131 elimine etmek ya da en aza indirgemek, h\u00fccresel d\u00fczeylere ila\u00e7 ta\u015f\u0131n\u0131m\u0131n\u0131 art\u0131rmak, d\u00fc\u015f\u00fck dozlarda etkin ve g\u00fcvenli tedavi sa\u011flamak, ila\u00e7lar\u0131n toksik ve immunojenik \u00f6zelliklerini en aza indirgemek, ila\u00e7 stabilitesini artt\u0131rmak, sa\u011fl\u0131kl\u0131 dokulara zarar vermeden hedef b\u00f6lgede istenilen d\u00fczeyde farmakolojik yan\u0131t elde etmek ama\u00e7land\u0131. Bu ama\u00e7la, dual hedef mant\u0131\u011f\u0131yla, asiyaloglikoprotein resept\u00f6r\u00fc ve manyetik olarak hedefli fonksiyonel nanopartik\u00fclleri i\u00e7eren form\u00fclasyon haz\u0131rlan\u0131lacak. Sentezlenecek manyetik nanopartik\u00fcller fonksiyonel hale getirilecek ve yap\u0131ya kemoterapi ilac\u0131 y\u00fcklenecek. Form\u00fclasyonun in vitro\/in vivo\/ex vivo testleri yap\u0131lacak ve karaci\u011fer kanseri tedavisinde kullan\u0131m potansiyeli ara\u015ft\u0131r\u0131lacak. Amac\u0131m\u0131z; karaci\u011fer kanser tedavisinde, sa\u011fl\u0131kl\u0131 h\u00fccrelere zarar vermeden direkt karaci\u011fer kanseri \u00fczerine etki ederek kanseri yok etmek\u201d dedi.<\/p>\n","protected":false},"excerpt":{"rendered":"
EGE \u00dcN\u0130VERS\u0130TES\u0130 (E\u00dc) FEN FAK\u00dcLTES\u0130 \u00d6\u011eRET\u0130M \u00dcYES\u0130 PROF. DR. \u015eENAY HAMARAT \u015eANLIER \u00d6NC\u00dcL\u00dc\u011e\u00dcNDE GEL\u0130\u015eT\u0130R\u0130LEN PROJE KAPSAMINDA, KARAC\u0130\u011eER KANSER\u0130N\u0130N TEDAV\u0130S\u0130NDE SA\u011eLIKLI H\u00dcCRELERE ZARAR VERMEDEN HEDEFL\u0130 \u0130LA\u00c7 TEDAV\u0130S\u0130 YAPILAB\u0130LMES\u0130 AMACIYLA \u00c7ALI\u015eMA BA\u015eLATILDI\u011eI A\u00c7IKLANDI.<\/p>\n","protected":false},"author":1,"featured_media":207944,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"jetpack_post_was_ever_published":false},"categories":[1],"tags":[13379,3032,3818,24582,21911,22177,3401,1456],"class_list":["post-207943","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-genel","tag-umutlandiran","tag-bilim","tag-binlerce","tag-insanlarindan","tag-kanserinde","tag-karaciger","tag-kisiyi","tag-proje"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"https:\/\/i0.wp.com\/www.tvturk.com\/wp-content\/uploads\/2019\/09\/bilim-insanlarindan-karaciger-kanserinde-binlerce-kisiyi-umutlandiran-proje_9fc4b0f.jpg?fit=1000%2C666","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/paKIfm-S5V","_links":{"self":[{"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/posts\/207943","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/comments?post=207943"}],"version-history":[{"count":0,"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/posts\/207943\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/media\/207944"}],"wp:attachment":[{"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/media?parent=207943"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/categories?post=207943"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/tags?post=207943"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}