Ankara \u00dcniversitesi T\u0131p Fak\u00fcltesi Endokrinoloji ve Metabolizma Hastal\u0131klar\u0131 Bilim Dal\u0131 \u00d6\u011fretim \u00dcyesi Prof. Dr. Mustafa \u015eahin, sinsi hastal\u0131klar aras\u0131nda yer alan ve genelde belirti g\u00f6stermeyen hipofiz t\u00fcm\u00f6r\u00fcne kar\u015f\u0131 toplumu duyarl\u0131 ve bilin\u00e7li olmaya \u00e7a\u011f\u0131rd\u0131.<\/p>\n
Ankara \u00dcniversitesi T\u0131p Fak\u00fcltesi Endokrinoloji ve Metabolizma Hastal\u0131klar\u0131 Bilim Dal\u0131 \u00d6\u011fretim \u00dcyesi Prof. Dr. Mustafa \u015eahin hipofiz bezi t\u00fcm\u00f6r\u00fc ile ilgili \u00f6nemli a\u00e7\u0131klamalarda bulundu. \u201cNormal olarak \u00e7al\u0131\u015ft\u0131\u011f\u0131 zaman hi\u00e7birimiz bu bezin varl\u0131\u011f\u0131n\u0131 bile hissetmeyiz. Ama hipofiz bezi hastal\u0131klar\u0131n\u0131n ki\u015finin hayat\u0131na inan\u0131lmaz derecede olumsuz etkileri olabilir\u201d diyen Prof. \u015eahin, hipofiz bezinin az \u00e7al\u0131\u015fmas\u0131 nedeniyle hipofiz yetmezli\u011fi olabilece\u011fi gibi, hipofiz bezinin fazla \u00e7al\u0131\u015fmas\u0131n\u0131n da bir\u00e7ok hipofiz t\u00fcm\u00f6r\u00fcnde g\u00f6r\u00fclebildi\u011fini s\u00f6yledi.<\/p>\n
V\u00fccudumuzda genellikle \u00e7ok k\u00fc\u00e7\u00fck miktarlarda hormon d\u00fczeylerinin \u00e7ok hassas ve dar normal aral\u0131klarda tutularak inanmas\u0131 g\u00fc\u00e7 bir denge sa\u011fland\u0131\u011f\u0131n\u0131 belirten \u015eahin, \u201cBeynin taban\u0131nda, optik sinirin hemen alt\u0131nda, T\u00fcrk E\u011feri denilen kemik bo\u015flu\u011funda yer alan daldaki kiraz gibi a\u015fa\u011f\u0131ya do\u011fru uzanan bezelye b\u00fcy\u00fckl\u00fc\u011f\u00fcnde \u00e7ok k\u00fc\u00e7\u00fck bir endokrin bezdir. Ama v\u00fccudumuzdaki bir\u00e7ok endokrin bezi ve hormonunu kontrol eder bu nedenle orkestra \u015fefi ya da y\u00f6netici bez olarak adland\u0131r\u0131l\u0131r. Bu kadar k\u00fc\u00e7\u00fck olup bu kadar \u00e7ok say\u0131da i\u015flem yapmas\u0131 inan\u0131lmazd\u0131r\u201d diye konu\u015ftu.<\/p>\n
T\u00fcrkiye\u2019de 100 bin civar\u0131nda hipofiz ile ili\u015fkili hastal\u0131\u011f\u0131 olan ki\u015fi oldu\u011funun tahmin edildi\u011fini belirten Prof. \u015eahin, bu hastalar\u0131n \u00e7o\u011funlu\u011funun yorgunluk, ba\u015f a\u011fr\u0131s\u0131, k\u0131s\u0131rl\u0131k, kilo al\u0131m\u0131 gibi m\u00fcphem ve sinsi \u015fikayetlere sahip oldu\u011funu s\u00f6yledi. Bir\u00e7ok hastan\u0131n hipofiz hastal\u0131klar\u0131na ba\u011fl\u0131 bu \u015fikayetlerin olabilece\u011fini bilmedi\u011fini ifade eden Prof. \u015eahin, \u201cBaz\u0131 hipofiz hastal\u0131klar\u0131nda 15 y\u0131la kadar do\u011fru tan\u0131 gecikebilir ve erken tan\u0131 hayati \u00f6neme sahiptir. Ayr\u0131ca, bu hastalar ya\u015fam boyu destek ve izlem gerektirir\u201d dedi.<\/p>\n
Teknoloji art\u0131\u015f\u0131 ile hipofiz t\u00fcm\u00f6rlerinin belirlenme s\u0131kl\u0131\u011f\u0131n\u0131n artt\u0131\u011f\u0131na i\u015faret eden Prof. \u015eahin, g\u00f6r\u00fcnt\u00fcleme teknikleri ile her 10 ki\u015fiden bir veya ikisinde rastgele hipofiz t\u00fcm\u00f6r\u00fc g\u00f6r\u00fclebildi\u011fini belirten Prof. \u015eahin \u015f\u00f6yle konu\u015ftu:<\/p>\n
\u201cBu t\u00fcm\u00f6rler k\u0131saca bir\u00e7ok ki\u015finin d\u00fc\u015f\u00fcnd\u00fc\u011f\u00fcnden \u00e7ok \u00e7ok daha s\u0131k g\u00f6r\u00fclen t\u00fcm\u00f6rlerdir. Bu t\u00fcm\u00f6rlerin hormon \u00fcretip \u00fcretmedi\u011fi ve hangilerinin cerrahi veya medikal tedaviye ihtiya\u00e7 duyaca\u011f\u0131n\u0131 belirlemek i\u00e7in endokrin uzman\u0131 kontrol\u00fc gereklidir. Genellikle hipofiz t\u00fcm\u00f6rleri y\u00fczde 99 oran\u0131nda iyi huylu t\u00fcm\u00f6rlerdir. T\u00fcm\u00f6r h\u00fccre tipine g\u00f6re e\u011fer kortizol hormonu salg\u0131lar ise Cushing Hastal\u0131\u011f\u0131 dedi\u011fimiz \u00f6zellikle kar\u0131n b\u00f6lgesinde kilo al\u0131m\u0131, aydede y\u00fcz dedi\u011fimiz yuvarlak y\u00fcz, kas g\u00fc\u00e7s\u00fczl\u00fc\u011f\u00fc, ense b\u00f6lgesinde ya\u011f birikimi, kan bas\u0131nc\u0131 y\u00fcksekli\u011fi ve kar\u0131n b\u00f6lgesinde geni\u015f mor y\u0131rt\u0131klar \u015feklinde kendini g\u00f6sterebilir. En s\u0131k olarak ise hipofiz t\u00fcm\u00f6rleri prolaktin dedi\u011fimiz memeden s\u00fct salg\u0131lanmas\u0131na neden olan hormonu salg\u0131lar ve kad\u0131nlarda adet d\u00fczensizli\u011fi ve s\u00fct gelmesi \u015fikayetierine yol a\u00e7abilir.\u201d<\/p>\n
Ba\u015f a\u011fr\u0131s\u0131na dikkat<\/p>\n
Hipofiz t\u00fcm\u00f6rlerinde g\u00f6rmede azalma, \u00e7ift g\u00f6rme, ba\u015f a\u011fr\u0131s\u0131 olabildi\u011finin alt\u0131n\u0131 \u00e7izen Prof. \u015eahin, \u201c\u00c7ocuklarda c\u00fccelik veya gigantizm g\u00f6r\u00fclebilir. Eri\u015fkinlerde ise akromegali dedi\u011fimiz el ve ayaklarda b\u00fcy\u00fcme, y\u00fcz\u00fck ve ayakkab\u0131 numaralar\u0131nda b\u00fcy\u00fcme, \u00e7enede \u00f6ne do\u011fru \u00e7\u0131k\u0131kl\u0131k, eklem a\u011fr\u0131lar\u0131, terleme \u015fikayetleri olan hastal\u0131k g\u00f6r\u00fclebilir. \u00c7ok sinsi ve yava\u015f ilerleyen bir hastal\u0131k oldu\u011fundan tan\u0131 genellikle \u00e7ok gecikir. Bu nedenle fark\u0131ndal\u0131k ve \u015f\u00fcphe \u00e7ok \u00f6nemlidir. Aile hekimleri ve di\u015f hekimlerinin de bu konudaki fark\u0131ndal\u0131k d\u00fczeyinin y\u00fcksek olmas\u0131 \u00e7ok \u00f6nemlidir. Hipofiz t\u00fcm\u00f6rleri ciddi hastal\u0131klard\u0131r fakat erken tan\u0131 ve uygun izlem ile sonu\u00e7lar \u00e7ok y\u00fcz g\u00fcld\u00fcr\u00fcc\u00fcd\u00fcr\u201d ifadelerini kulland\u0131.<\/p>\n
Hipofiz bezinin i\u015fleviyle ilgili bilgi veren Prof. \u015eahin, \u201cHipofiz bezinin salg\u0131lad\u0131\u011f\u0131 hormonlar\u0131n dola\u015f\u0131ma kat\u0131larak tiroid bezinden tiroid hormonlar\u0131n\u0131n \u00fcretilip sal\u0131nmas\u0131n\u0131 b\u00f6ylece metabolizma h\u0131z\u0131n\u0131 ayarlarken, b\u00f6brek \u00fcst\u00fc bezinden hayat i\u00e7in gerekli bir hormon olan kortizol salg\u0131lanmas\u0131n\u0131 bu sayede strese kar\u015f\u0131 koyabilmemizi, kan bas\u0131nc\u0131m\u0131z\u0131n yeterli d\u00fczeyde olmas\u0131n\u0131 sa\u011flar. Testis veya yumurtal\u0131klar\u0131 uyararak cinsel ve \u00fcreme fonksiyonlar\u0131n\u0131 sa\u011flar, prolaktin isimli hormon ile emzirmeyi sa\u011flar. Hipofiz bezi salg\u0131lad\u0131\u011f\u0131 b\u00fcy\u00fcme hormonu ile b\u00fcy\u00fcmeyi ve hormonun di\u011fer yararl\u0131 etkilerini sa\u011flar. Hipofiz bezi termostat gibidir. V\u00fccudu \u00e7ok yak\u0131ndan takip eder ve gerekli g\u00f6rd\u00fc\u011f\u00fcnde sinyaller g\u00f6ndererek de\u011fi\u015fmesi gereken durumlar\u0131 de\u011fi\u015ftirir. V\u00fccudumuzda \u00e7ok k\u00fc\u00e7\u00fck miktarlarda hormon d\u00fczeylerini hassas normal aral\u0131klar i\u00e7erisinde tutarak inan\u0131lmaz bir denge sa\u011flanmaktad\u0131r\u201d dedi.<\/p>\n
15. Hipofiz Sempozyumu Ankara\u2019da d\u00fczenleniyor<\/p>\n
Ankara \u00dcniversitesi T\u0131p Fak\u00fcltesi, Endokrinoloji ve Metabolizma Bilim Dal\u0131 \u00f6nc\u00fcl\u00fc\u011f\u00fcnde T\u00fcrkiye Endokrinoloji ve Metabolizma Hastal\u0131klar\u0131 Derne\u011fi\u2019nin katk\u0131lar\u0131 ile 8 – 9 Kas\u0131m 2019 tarihleri aras\u0131nda 15. Hipofiz Sempozyumu d\u00fczenlenecek. Sheraton Otel Ankara\u2019da en se\u00e7kin ve deneyimli endokrinologlar, cerrahlar, n\u00f6roradyologlar bilimsel konular\u0131 tart\u0131\u015farak, deneyimlerini payla\u015fma f\u0131rsat\u0131 bulacaklar. Ayr\u0131ca ikincisi yap\u0131lan hipofiz g\u00f6r\u00fcnt\u00fcleme kursu ile de olgular e\u015fli\u011finde bu konudaki bilgi birikimleri ve deneyimler payla\u015f\u0131lacak.<\/p>\n","protected":false},"excerpt":{"rendered":"
ANKARA \u00dcN\u0130VERS\u0130TES\u0130 TIP FAK\u00dcLTES\u0130 ENDOKR\u0130NOLOJ\u0130 VE METABOL\u0130ZMA HASTALIKLARI B\u0130L\u0130M DALI \u00d6\u011eRET\u0130M \u00dcYES\u0130 PROF. DR. MUSTAFA \u015eAH\u0130N S\u0130NS\u0130 HASTALIKLAR ARASINDA YER ALAN VE GENELDE BEL\u0130RT\u0130 G\u00d6STERMEYEN H\u0130POF\u0130Z T\u00dcM\u00d6R\u00dcNE KAR\u015eI TOPLUMU DUYARLI VE B\u0130L\u0130N\u00c7L\u0130 OLMAYA \u00c7A\u011eIRDI.<\/p>\n","protected":false},"author":1,"featured_media":223905,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[1],"tags":[16126,56601,2541,24776,42199,6810,6809],"class_list":["post-223904","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-genel","tag-hastalik","tag-hipofiz","tag-karsi","tag-sinsi","tag-tumorune","tag-uyariyor","tag-uzmanlar"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"https:\/\/i0.wp.com\/www.tvturk.com\/wp-content\/uploads\/2019\/11\/sinsi-hastalik-hipofiz-tumorune-karsi-uzmanlar-uyariyor_9c1be2e.jpg?fit=741%2C916","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/paKIfm-Wfm","_links":{"self":[{"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/posts\/223904","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/comments?post=223904"}],"version-history":[{"count":0,"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/posts\/223904\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/media\/223905"}],"wp:attachment":[{"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/media?parent=223904"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/categories?post=223904"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/tags?post=223904"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}