Prof. Dr. Murat T\u00f6r\u00fcner, d\u0131\u015fk\u0131 nakli y\u00f6nteminin clostridioides difficile enfeksiyonuna ba\u011fl\u0131 ishalleri tamamen ge\u00e7irilebilece\u011fini belirterek, \u201cDi\u011fer tedavilerde kullan\u0131ld\u0131\u011f\u0131nda elimizde hala tutabilece\u011fimiz kan\u0131t yok. Sadece clostridioides difficile enfeksiyonunda elimizde kan\u0131t var\u201d dedi.<\/p>\n
T\u00fcrk Gastroenteroloji Derne\u011finin ev sahipli\u011finde d\u00fczenlenen \u201c36. UGH 2019 Mezuniyet Sonras\u0131 E\u011fitim” toplant\u0131s\u0131na kat\u0131lan Ankara \u00dcniversitesi T\u0131p Fak\u00fcltesi Gastroenteroloji Bilim Dal\u0131 \u00d6\u011fretim \u00dcyesi Prof. Dr. Murat T\u00f6r\u00fcner, d\u0131\u015fk\u0131 nakli (gaita nakli) hakk\u0131nda a\u00e7\u0131klamalarda bulundu. T\u00f6r\u00fcner, d\u0131\u015fk\u0131 naklinin \u00e7ok pop\u00fcler oldu\u011funu ve pek \u00e7ok \u00e7al\u0131\u015fmalar\u0131n da oda\u011f\u0131 olan bir tedavi \u015fekli oldu\u011funu kaydetti. D\u0131\u015fk\u0131 naklinin yeni bir tedavi y\u00f6ntemi olmad\u0131\u011f\u0131n\u0131n alt\u0131n\u0131 \u00e7izen T\u00f6r\u00fcner, bu tedavinin tarih\u00e7esinin milattan \u00f6nceye dayand\u0131\u011f\u0131n\u0131 belirtti. D\u0131\u015fk\u0131 naklinin ilk olarak \u00c7in t\u0131bb\u0131nda kullan\u0131ld\u0131\u011f\u0131n\u0131 dile getiren Prof. Dr. T\u00f6r\u00fcner, \u201cSar\u0131 \u00e7orba tedavisi diye an\u0131lm\u0131\u015f. Onlar da insan d\u0131\u015fk\u0131s\u0131n\u0131 suland\u0131rarak insanlara i\u00e7irmi\u015f. Daha sonra uzun bir s\u00fcre Do\u011fu t\u0131bb\u0131nda kullan\u0131lm\u0131\u015f. Bat\u0131 t\u0131bb\u0131na girmesi 1950\u2019lerde ba\u015flad\u0131. \u2018Clostridioides difficile\u2019 bakterisi var. Antibiyotik alanlarda ishal sebebi oluyor. Bu enfeksiyonun tedavisinde kullan\u0131lmaya ba\u015fland\u0131. D\u0131\u015fk\u0131 nakli 2010\u2019larda hem ABD\u2019de, hem de Avrupa\u2019da sadece bu bakteri enfeksiyonuna ba\u011fl\u0131 ishal tedavilerinde sa\u011fl\u0131k bakanl\u0131klar\u0131nca onaylanm\u0131\u015f bir tedavi y\u00f6ntemi. Ba\u015fka bir hastal\u0131kta onayl\u0131 bir tedavi de\u011fil. Bir bakteri var, bu bakteriye ba\u011fl\u0131 inat\u00e7\u0131 ishaller tedavide birinci basamak de\u011fil. Antibiyoti\u011fe diren\u00e7 varsa o zaman d\u0131\u015fk\u0131 nakli yap\u0131lmas\u0131na izin veriliyor. Bunun d\u0131\u015f\u0131ndaki t\u00fcm hastal\u0131klarda deneme a\u015famas\u0131nda olan bir tedavi \u015fekli\u201d dedi.<\/p>\n
Tedaviyle ilgili \u00e7ok say\u0131da \u00e7al\u0131\u015fman\u0131n yap\u0131ld\u0131\u011f\u0131n\u0131 aktaran T\u00f6r\u00fcner, bu \u00e7al\u0131\u015fmalar\u0131n baz\u0131lar\u0131n\u0131n olumlu, baz\u0131lar\u0131n\u0131n ise olumsuz sonu\u00e7 verdi\u011fini s\u00f6yledi.<\/p>\n
\u201cHastan\u0131n \u00f6l\u00fcm\u00fcyle sonu\u00e7land\u0131\u201d<\/p>\n
D\u0131\u015fk\u0131 naklinin basit bir tedavi y\u00f6ntemi olmad\u0131\u011f\u0131n\u0131n alt\u0131n\u0131 \u00e7izen T\u00f6r\u00fcner, s\u00f6zlerine \u015f\u00f6yle devam etti:<\/p>\n
\u201cBu esas\u0131nda d\u0131\u015fk\u0131 naklinden \u00f6te bir biyolojik ve genetik bir tedavi s\u0131n\u0131f\u0131na al\u0131nm\u0131\u015f. Bunu yaparken baz\u0131 kriterleri mutlaka g\u00f6zetmemiz gerekiyor. Ge\u00e7ti\u011fimiz y\u0131l Amerika\u2019da iki tane d\u0131\u015fk\u0131 nakli yap\u0131lm\u0131\u015f hasta \u00e7ok ciddi olarak hastaland\u0131. Hatta hastalardan birisi maalesef hayat\u0131n\u0131 kaybetti. Verilen d\u0131\u015fk\u0131dan gelen bakteri, al\u0131c\u0131n\u0131n kan\u0131na kar\u0131\u015ft\u0131 ve hastan\u0131n \u00f6l\u00fcm\u00fcyle sonu\u00e7land\u0131. Dolay\u0131s\u0131yla Amerika\u2019da bu \u00e7al\u0131\u015fmalar bir ara durduruldu, yeni kriterler getirilmeye \u00e7al\u0131\u015f\u0131l\u0131yor. Kula\u011fa basit bir tedavi gibi geliyor ama gidilmesi gereken uzun bir yol var.\u201d<\/p>\n
T\u00f6r\u00fcner, T\u00fcrk Gastroenteroloji Derne\u011fi olarak d\u0131\u015fk\u0131 nakliyle ilgili \u00e7al\u0131\u015fmalar\u0131n belirli kriterlere g\u00f6re yap\u0131lmas\u0131 gerekti\u011fini uygun g\u00f6rd\u00fcklerini ifade etti.<\/p>\n
\u201cYeterince kan\u0131t olmal\u0131\u201d<\/p>\n
Konuyla ilgili hastalardan yaz\u0131l\u0131 onay formu al\u0131narak, olas\u0131 yan etkilerin anlat\u0131lmas\u0131 ve hastan\u0131n detayl\u0131 bir \u015fekilde bilgilendirilmesi gerekti\u011fine dikkat \u00e7eken Prof. Dr. Murat T\u00f6r\u00fcner, \u201cHastalar onay verdikten sonra bunlar yap\u0131lmal\u0131. Yararl\u0131 her \u015feyin herkese yararl\u0131 olaca\u011f\u0131n\u0131n d\u00fcnyada garantisi yoktur. Yararl\u0131 olan \u015feyi \u00e7ok fazla t\u00fcketirsek, \u00e7ok fazla yarar al\u0131r\u0131z diye bir \u015fey de yok. Dolay\u0131s\u0131yla mutlaka kan\u0131ta dayal\u0131 t\u0131p yapmam\u0131z gerekiyor. Hastalar bize sordu\u011funda elimizde yeterince kan\u0131t\u0131n olmas\u0131 gerekiyor. Yoksa \u2018Ay\u015fe Han\u0131m\u2019a iyi geldi, Mehmet Bey\u2019e de iyi gelecek\u2019 diye bir felsefeyle tedavi yapmamam\u0131z gerekiyor\u201d ifadelerini kullan\u0131ld\u0131.<\/p>\n
D\u0131\u015fk\u0131 nakli tedavisi y\u00f6ntemiyle clostridioides difficile enfeksiyonuna ba\u011fl\u0131 ishallerin tamamen ge\u00e7ebilece\u011fini bildiren T\u00f6r\u00fcner, \u201cBu d\u0131\u015fk\u0131 naklini yapt\u0131\u011f\u0131n\u0131z zaman hasta tamamen sa\u011fl\u0131\u011f\u0131na kavu\u015fuyor. Di\u011fer tedavilerde kullan\u0131ld\u0131\u011f\u0131nda elimizde hala tutabilece\u011fimiz kan\u0131t yok. Sadece clostridioides difficile enfeksiyonunda elimizde kan\u0131t var\u201d dedi.<\/p>\n","protected":false},"excerpt":{"rendered":"
SON YILLARDA TIBBIN \u00dcZER\u0130NDE DURDU\u011eU, \u2018DI\u015eKI NAKL\u0130\u2019 TEDAV\u0130 Y\u00d6NTEM\u0130 HAKKINDA B\u0130LG\u0130LEND\u0130RMELERDE BULUNAN PROF. DR. MURAT T\u00d6R\u00dcNER, DI\u015eKI NAKL\u0130 TEDAV\u0130S\u0130 Y\u00d6NTEM\u0130YLE, CLOSTR\u0130D\u0130O\u0130DES D\u0130FF\u0130C\u0130LE ENFEKS\u0130YONUNA BA\u011eLI \u0130SHALLER\u0130N TAMAMEN GE\u00c7\u0130R\u0130LEB\u0130LECE\u011e\u0130N\u0130 BEL\u0130RTT\u0130. T\u00d6R\u00dcNER, \u201cD\u0130\u011eER TEDAV\u0130LERDE KULLANILDI\u011eINDA EL\u0130M\u0130ZDE HALA TUTAB\u0130LECE\u011e\u0130M\u0130Z KANIT YOK. SADECE CLOSTR\u0130D\u0130O\u0130DES D\u0130FF\u0130C\u0130LE ENFEKS\u0130YONUNDA EL\u0130M\u0130ZDE KANIT VAR\u201d DED\u0130.<\/p>\n","protected":false},"author":1,"featured_media":235382,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"jetpack_post_was_ever_published":false},"categories":[1],"tags":[50757,606,1432,12189],"class_list":["post-235381","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-genel","tag-diski","tag-hayat","tag-kurtariyor","tag-nakli"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"https:\/\/i0.wp.com\/www.tvturk.com\/wp-content\/uploads\/2019\/12\/diski-nakli-hayat-kurtariyor_e1164a8.jpg?fit=1000%2C870","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/paKIfm-Zet","_links":{"self":[{"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/posts\/235381","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/comments?post=235381"}],"version-history":[{"count":0,"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/posts\/235381\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/media\/235382"}],"wp:attachment":[{"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/media?parent=235381"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/categories?post=235381"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/tags?post=235381"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}