D\u00fcnyada son d\u00f6nemde yayg\u0131nla\u015fan ki\u015fiselle\u015ftirilmi\u015f t\u0131p ile ilgili Dr. Sibel \u00d6zg\u00fcl, “Ki\u015fiselle\u015ftirilmi\u015f t\u0131p yakla\u015f\u0131m\u0131 ile ger\u00e7ekle\u015ftirilen farmakogenetik analizler \u00e7o\u011fu durumda hangi hastada hangi ilac\u0131n yarar sa\u011flayaca\u011f\u0131n\u0131 bize \u00f6nceden s\u00f6yler” dedi.<\/p>\n
Ki\u015fiselle\u015ftirilmi\u015f T\u0131p Doktoru Sibel \u00d6zg\u00fcl, do\u011fru tedavi i\u00e7in her bireyin \u2019ila\u00e7 pasaportu\u2019 olmas\u0131n\u0131n \u00f6nemine de\u011finerek, “\u0130la\u00e7lar i\u00e7in kullan\u0131lan NNT (Number Needed to Treat) denen bir kavram var. K\u0131saca, “Ka\u00e7 hastay\u0131 tedavi edersek, bir tanesi ilave yarar g\u00f6r\u00fcr” sorusunun cevab\u0131d\u0131r bu. \u00d6rne\u011fin NNT de\u011feri 20 olan bir ila\u00e7 d\u00fc\u015f\u00fcn\u00fcn. Bunun anlam\u0131, 20 hasta bu ilac\u0131 kullan\u0131rsa bir tanesinin yarar g\u00f6rmesidir. Di\u011ferleri yarar g\u00f6rmedikleri gibi, bir de yan etki g\u00f6rebiliyorlar. Farmakogenetik, ila\u00e7 etkinli\u011finin genetik yap\u0131ya ve dolay\u0131s\u0131yla bireylere g\u00f6re de\u011fi\u015fimini inceleyen bir bilim dal\u0131d\u0131r. Size \u00f6zel haz\u0131rlanacak bir ila\u00e7 pasaportu ile kullanaca\u011f\u0131n\u0131z a\u011fr\u0131 kesiciden, antibiyoti\u011fe, kanser durumunda alaca\u011f\u0131n\u0131z kemoterapiye kadar geneti\u011finize g\u00f6re uygun t\u00fcm ila\u00e7lar\u0131 belirleyebiliyoruz. Ki\u015fiselle\u015ftirilmi\u015f t\u0131p yakla\u015f\u0131m\u0131 ile ger\u00e7ekle\u015ftirilen farmakogenetik analizler \u00e7o\u011fu durumda hangi hastada hangi ilac\u0131n yarar sa\u011flayaca\u011f\u0131n\u0131 bize \u00f6nceden s\u00f6yler. Bu sayede hem ila\u00e7 maruziyetinin \u00f6n\u00fcne ge\u00e7er ve olas\u0131 gereksiz yan etkiler \u00f6nlenmi\u015f olur, hem de gereksiz tedavi maliyetinin \u00f6n\u00fcne ge\u00e7ilmi\u015f olur” dedi.<\/p>\n
Ki\u015fiselle\u015ftirilmi\u015f t\u0131p nedir?<\/p>\n
Ki\u015fiselle\u015ftirilmi\u015f t\u0131p uygulamalar\u0131nda, ba\u015fta genetik analizler olmak \u00fczere bir\u00e7ok tan\u0131 y\u00f6ntemi ve sonras\u0131nda da tedavi yakla\u015f\u0131mlar\u0131 ki\u015fiye \u00f6zg\u00fc olarak uyguland\u0131\u011f\u0131 belirtiliyor.<\/p>\n
Ayn\u0131 hastal\u0131\u011fa sahip iki hasta, ayn\u0131 tedaviye ayn\u0131 cevab\u0131 vermedi\u011fi gibi, ayn\u0131 ila\u00e7lar\u0131n hastalar aras\u0131nda farkl\u0131 etki g\u00f6sterece\u011fi ger\u00e7e\u011fi, \u0130la\u00e7 Pasaportu\u2019nun \u00f6nemini ortaya koyuyor. Bug\u00fcn art\u0131k t\u0131pta gelinen nokta farmakogenetik testi ile ila\u00e7lar\u0131n hastan\u0131n genine uygun olup olmad\u0131\u011f\u0131n\u0131n saptanmas\u0131. Bu durum art\u0131k hastan\u0131n tedavisi i\u00e7in kendi ki\u015fisel k\u0131lavuzu olan ila\u00e7 pasaportunu ki\u015fisel t\u0131p doktoru ile olu\u015fturmas\u0131na olanak sa\u011fl\u0131yor.<\/p>\n","protected":false},"excerpt":{"rendered":"
K\u0130\u015e\u0130SELLE\u015eT\u0130R\u0130LM\u0130\u015e TIP DOKTORU S\u0130BEL \u00d6ZG\u00dcL<\/p>\n","protected":false},"author":1,"featured_media":244691,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[1],"tags":[60967,619,73,44,3712,44028,144],"class_list":["post-244690","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-genel","tag-bireye","tag-dogru","tag-her","tag-icin","tag-ilac","tag-pasaportu","tag-tedavi"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"https:\/\/i0.wp.com\/www.tvturk.com\/wp-content\/uploads\/2019\/12\/dogru-tedavi-icin-her-bireye-ilac-pasaportu_17b5793.jpg?fit=666%2C1000","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/paKIfm-11EC","_links":{"self":[{"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/posts\/244690","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/comments?post=244690"}],"version-history":[{"count":0,"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/posts\/244690\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/media\/244691"}],"wp:attachment":[{"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/media?parent=244690"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/categories?post=244690"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/tags?post=244690"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}