Do\u00e7. Dr. Hikmet Tekin Nacaro\u011flu, son y\u0131llarda alerjik rinit, g\u0131da alerjisi, alerjik egzama ve ast\u0131m\u0131n giderek artt\u0131\u011f\u0131na dikkat \u00e7ekerek, “Baz\u0131 tedaviye yan\u0131ts\u0131z, spesifik bir alerjene kar\u015f\u0131 duyarl\u0131l\u0131\u011f\u0131 deri testi ve kan testleri ile belirlenmi\u015f, klinik bulgular\u0131 da testlerle uyumlu olan hastalarda a\u015f\u0131lama yap\u0131labilir.” dedi.<\/p>\n
Medipol Mega \u00dcniversite Hastanesi \u00c7ocuk \u0130mm\u00fcnoloji ve Alerji Hastal\u0131klar\u0131 B\u00f6l\u00fcm\u00fcnden Do\u00e7. Dr. Hikmet Tekin Nacaro\u011flu, y\u00fczy\u0131ldan fazlad\u0131r kullan\u0131lan alerji a\u015f\u0131lar\u0131na ili\u015fkin \u00f6nemli a\u00e7\u0131klamalarda bulundu. Dr. Nacaro\u011flu, son y\u0131llarda alerjik rinit, g\u0131da alerjisi, alerjik egzama ve ast\u0131m\u0131n giderek artt\u0131\u011f\u0131na dikkati \u00e7ekerek “\u00d6zellikle ast\u0131m ve alerjik rinitte yani saman nezlesinde ilk planda alerji ila\u00e7lar\u0131, burun damlalar\u0131 gibi semptomlara y\u00f6nelik tedaviler kullan\u0131l\u0131r. Baz\u0131 tedaviye yan\u0131ts\u0131z, spesifik bir alerjene kar\u015f\u0131 duyarl\u0131l\u0131\u011f\u0131 deri testi ve kan testleri ile belirlenmi\u015f, klinik bulgular\u0131 da testlerle uyumlu olan hastalarda a\u015f\u0131lama yap\u0131labilir. Bu alerjen spesifik imm\u00fcnoterapi olarak isimlendirilir. A\u015f\u0131 tedavisi; deri ve kan testi ile g\u00f6sterilen alerjen maddenin ki\u015fide yak\u0131nmalara neden olmas\u0131, alerjenden korunma ve ila\u00e7 tedavisinden yeterli fayda g\u00f6rmemi\u015f olmas\u0131, ki\u015finin uzun s\u00fcreli ila\u00e7 tedavisi istememesi durumlar\u0131nda kullan\u0131l\u0131yor.” dedi.<\/p>\n
“Belirli aral\u0131klarla doz art\u0131r\u0131l\u0131r”<\/p>\n
\u0130ki \u00e7e\u015fit a\u015f\u0131lama oldu\u011funu belirten Dr. Nacaro\u011flu, \u015fu bilgileri verdi: “A\u015f\u0131laman\u0131n ilk \u00e7e\u015fidi subkutan imm\u00fcnoterapi olarak isimlendirilen cilt alt\u0131na alerjen ekstresinin enjekte edilmesiyle uygulan\u0131r. Bu y\u00f6ntemde d\u00fc\u015f\u00fck doz a\u015f\u0131lama ile ba\u015flanarak belirli aral\u0131klarla dozlar art\u0131r\u0131l\u0131r. Farkl\u0131 tedavi protokollerine g\u00f6re haftal\u0131k, 15 g\u00fcnl\u00fck, 1 ayl\u0131k aralarla a\u015f\u0131lama yap\u0131l\u0131r. 3-5 y\u0131l devam edilir, ideali ise 5 y\u0131l a\u015f\u0131lamad\u0131r. Bu y\u00f6ntemle ot polenleri, ev tozu akarlar\u0131, k\u00fcf mantarlar\u0131, \u00e7e\u015fitli a\u011fa\u00e7 polenleri, kedi t\u00fcy\u00fc gibi hayvan epitellerine kar\u015f\u0131 a\u015f\u0131lama yap\u0131labilir. A\u015f\u0131lama s\u0131ras\u0131nda v\u00fccutta kurde\u015fen benzeri d\u00f6k\u00fcnt\u00fcler, a\u015f\u0131 uygulanan yerde \u015fi\u015flik, k\u0131zar\u0131kl\u0131k, solunum s\u0131k\u0131nt\u0131s\u0131 ve nadiren hayat\u0131 tehdit edici anafilaksi olarak tan\u0131mlanan \u00e7e\u015fitli alerjik reaksiyonlar g\u00f6zlenebilir. Bu nedenle cilt alt\u0131 a\u015f\u0131lama mutlaka gerekli m\u00fcdahalenin yap\u0131labilece\u011fi doktor bulunan bir hastane ortam\u0131 veya sa\u011fl\u0131k merkezinde uygulanmal\u0131. \u00d6zellikle hastal\u0131\u011f\u0131n alevlendi\u011fi d\u00f6nemlerde veya yeni \u015fi\u015feye ge\u00e7ildi\u011fi d\u00f6nemlerde reaksiyon riski artmakta.”<\/p>\n
“Dil alt\u0131 y\u00f6nteminin riski daha d\u00fc\u015f\u00fck”<\/p>\n
Dr. Nacaro\u011flu, ikinci a\u015f\u0131lama y\u00f6ntemini ise \u015f\u00f6yle a\u00e7\u0131klad\u0131: “Sublingual\/oral imm\u00fcnoterapi olarak bilinen y\u00f6ntemde spesifik bir alerjeni belirlenen ve semptomatik tedavilere yan\u0131ts\u0131z olan hastalarda tablet veya damla \u015feklinde haz\u0131rlanm\u0131\u015f dil alt\u0131 preparatlar\u0131 her g\u00fcn 3 y\u0131l boyunca kullan\u0131l\u0131r. \u0130lk birka\u00e7 doz hastanede uyguland\u0131ktan sonra hasta evde uygulamaya devam eder. Ortaya \u00e7\u0131kan yan etkiler genelde a\u011f\u0131zda ka\u015f\u0131nt\u0131 ve irritasyondur, genellikle tedavinin devam\u0131nda kaybolur. Ses k\u0131s\u0131kl\u0131\u011f\u0131, bo\u011fulma hissi ve nefes alamama gibi ciddi yan etki olas\u0131l\u0131\u011f\u0131 \u00e7ok d\u00fc\u015f\u00fck. Her iki tedavi y\u00f6ntemi i\u00e7in de tedavinin ba\u015far\u0131s\u0131 d\u00fczenli uygulamaya ba\u011fl\u0131d\u0131r. Doz a\u015f\u0131mlar\u0131 ve ara verme tedavinin ba\u015far\u0131s\u0131n\u0131 d\u00fc\u015f\u00fcr\u00fcr.”<\/p>\n
“5 ya\u015f\u0131ndan k\u00fc\u00e7\u00fcklere verilemez”<\/p>\n
A\u015f\u0131 tedavisinin hem tedavi edici hem de koruyucu etkisi bulundu\u011funa de\u011finen Dr. Nacaro\u011flu, \u015fu de\u011ferlendirmeyi yapt\u0131: “Alerjik hastal\u0131\u011f\u0131n do\u011fal seyrini de\u011fi\u015ftiren tek tedavi y\u00f6ntemidir. Tedaviye uyumsuz hastalara, 5 ya\u015f\u0131ndan k\u00fc\u00e7\u00fck \u00e7ocuklara, a\u011f\u0131r ast\u0131ml\u0131lara, kanser, ba\u011f\u0131\u015f\u0131kl\u0131k sistemi hastal\u0131klar\u0131, psikolojik bozukluk, ciddi hipertansiyon ve kalp hastal\u0131\u011f\u0131 durumlar\u0131nda a\u015f\u0131 tedavisi verilemez. Hamile oldu\u011fu bilinen hastalara a\u015f\u0131 tedavisi ba\u015flanmaz ama zaten a\u015f\u0131 almakta olan hasta gebe kald\u0131ysa tedaviye devam edebilir. A\u015f\u0131 tedavisinin anneye veya bebe\u011fe bir zarar\u0131 yoktur. A\u015f\u0131 sonras\u0131 lokal veya genel yan etkiler olabilir. Enjeksiyon uygulanan yerde madeni bir para b\u00fcy\u00fckl\u00fc\u011f\u00fcnde k\u0131zar\u0131kl\u0131k, ka\u015f\u0131nt\u0131 ve \u015fi\u015flik olmas\u0131 normaldir. \u00c7ap\u0131 5 cm ve \u00fcst\u00fcndeki reaksiyonlarda, hasta bir s\u00fcre g\u00f6zetim alt\u0131nda tutulur, lokal buz uygulamas\u0131 ve antihistaminik ila\u00e7 verilir. Lokal yan etkilere g\u00f6re \u00e7ok daha nadir olsa da t\u00fcm v\u00fccudu etkileyen yan etkiler ilk 24 saatte ortaya \u00e7\u0131kabilir. Ka\u015f\u0131nt\u0131l\u0131 kabar\u0131kl\u0131klar, dil veya dudakta \u015fi\u015fme, nefes darl\u0131\u011f\u0131, ses k\u0131s\u0131kl\u0131\u011f\u0131, g\u00f6\u011f\u00fcste s\u0131k\u0131\u015fma hissi, burun ak\u0131nt\u0131s\u0131, tansiyon d\u00fc\u015f\u00fckl\u00fc\u011f\u00fc ve \u015fuur kayb\u0131 olu\u015fabilir. B\u00f6yle durumlarda hasta en yak\u0131n sa\u011fl\u0131k merkezine veya kendi alerji hekimine ba\u015fvurmal\u0131d\u0131r. A\u015f\u0131n\u0131n ila\u00e7lar\u0131n aksine i\u00e7 organlara zarar verici yan etkisi yoktur. \u0130\u00e7inde ila\u00e7 veya kortizon bulunmamaktad\u0131r, kilo ald\u0131rmaz. A\u015f\u0131lar evde muhafaza ediliyorsa buzdolab\u0131nda raf k\u0131sm\u0131nda bulundurulmal\u0131. Kesinlikle buzlu\u011fa koyulmamal\u0131 ve dondurulmamal\u0131. A\u015f\u0131 yap\u0131ld\u0131ktan sonra s\u0131cak banyo, sauna, uzun s\u00fcreli du\u015ftan ve a\u011f\u0131r fiziksel aktivitelerden uzak durulmal\u0131. A\u015f\u0131lar d\u00fczenli olarak planland\u0131\u011f\u0131 g\u00fcnlerde yapt\u0131r\u0131lmal\u0131. A\u015f\u0131 tedavisi aksat\u0131ld\u0131\u011f\u0131nda tedavi yetersiz veya ba\u015far\u0131s\u0131z olacakt\u0131r.”<\/p>\n","protected":false},"excerpt":{"rendered":"
DO\u00c7. DR. H\u0130KMET TEK\u0130N NACARO\u011eLU, SON YILLARDA ALERJ\u0130K R\u0130N\u0130T, GIDA ALERJ\u0130S\u0130, ALERJ\u0130K EGZAMA VE ASTIMIN G\u0130DEREK ARTTI\u011eINA D\u0130KKAT \u00c7EKT\u0130<\/p>\n","protected":false},"author":1,"featured_media":246575,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"jetpack_post_was_ever_published":false},"categories":[1],"tags":[57852,11567,19835,1084,25593,6552,366,17259],"class_list":["post-246574","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-genel","tag-alerjinin","tag-asi","tag-degistiren","tag-dogal","tag-seyrini","tag-tedavisi","tag-tek","tag-yontem"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"https:\/\/i0.wp.com\/www.tvturk.com\/wp-content\/uploads\/2019\/12\/alerjinin-dogal-seyrini-degistiren-tek-yontem-asi-tedavisi_b7f7840.jpg?fit=1000%2C665","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/paKIfm-1290","_links":{"self":[{"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/posts\/246574","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/comments?post=246574"}],"version-history":[{"count":0,"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/posts\/246574\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/media\/246575"}],"wp:attachment":[{"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/media?parent=246574"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/categories?post=246574"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.tvturk.com\/index.php\/wp-json\/wp\/v2\/tags?post=246574"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}